Forensic Phenotyping
The Future of Identification

                  
ISAS™  
 

ISAS™ software is a comprehensive platform for phenotypic screening that allows investigators to generate far more detailed investigative leads from DNA samples than has previously been possible.

Powerful all-in-one solution

ISAS™ employs a computationally powerful approach that examines single nucleotide polymorphisms (SNPs) to develop a profile that describes the physical appearance of an individual.  This comprehensive test creates highly specific phenotypic predictions from a single DNA sample, combining data related to:
  • biogeographic ancestry
  • relatedness/kinship analysis
  • gender
  • Y and mitochondrial haplotype
  • physical appearance (hair color, eye color, etc.)

When an individual’s genetic profile is not present in existing criminal databases (such as CODIS), investigators have traditionally had limited options to gain meaningful insights from the DNA evidence.   In such cases, the aggregate SNP profile is able to push beyond these limitations to predict an image of the subject, along with information about their recent environment (e.g. by the presence of non-human DNA evidence in the case of a dog owner), with a high degree of accuracy.

Cost effective, requiring less DNA

Because the comprehensive SNP panel can be run using a single DNA aliquot for all tests, ISAS™ requires less DNA than traditional approaches, saving valuable DNA, as well as time and money.

Results you can trust

ISAS™ uses advanced anthropometric and statistical methodology to evaluate each SNP against large-scale genomic and phenotypic reference datasets. For each variable analyzed, ISAS™ generates a quality score that enables investigators to assess the reliability of that particular prediction.  This allows investigators to prioritize information extracted and proceed with greater certainty about the results of the analysis.

Easy to use, easy to interpret

ISAS™ provides rapid, automated analysis of genotyping data.  The software generates comprehensive reports that have a simple, straightforward, and highly informative interface (click here to see a sample report).

Flexible solutions

Identitas offers multiple options ranging from turn-key solutions to installation of the ISAS™ software directly at a client’s site. 

Option Genotyping Data Analysis
ISAS™ Turn-key Client submits DNA directly to one of our preferred service providers Data analysis done at Identitas; client receives detailed report of results
ISAS™ Hybrid Genotyping data generated by the client or a third party of the client’s choosing. Data analysis done at Identitas; client receives detailed report of results
ISAS™ Desktop App Genotyping data generated and maintained by the client. ISAS™ installed at client site as a desktop application. Data input and automated analysis completed in-house at the client site. Optional technical support available.
Custom analysis In addition to the proprietary ISAS™ SNP panel, custom SNPs can be added to interrogate specific client requests Custom data analysis is available on a fee-for-service basis
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